A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/535 (2006.01) A61K 31/55 (2006.01) A61K 31/553 (2006.01) A61P 35/02 (2006.01) C07D 487/04 (2006.01) C07D 487/14 (2006.01) C07D 498/22 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2462657
The present invention relates to the use of staurosporines derivatives for the preparation of a drug for the treatment of diseases involving deregulated FLT3 receptor tyrosine kinase activity, especially for the curative and/or prophylactic treatment of leukemias and myelodysplastic syndromes, and to a method of treating diseases involving deregulated FLT3 receptor tyrosine kinase activity.
La présente invention concerne l'utilisation de dérivés de staurosporine dans la préparation d'un médicament administré dans le traitement des maladies associées à un déréglement de l'activité tyrosine kinase du récepteur FLT3, en particulier le traitement curatif et/ou prophylactique des leucémies et des syndromes myélodysplasiques, et une méthode de traitement des maladies associées à un déréglement de l'activité tyrosine kinase du récepteur FLT3.
Griffin James Douglas
Manley Paul William
Dana-Farber Cancer Institute Inc.
Fetherstonhaugh & Co.
Novartis Ag
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