C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/078 (2010.01) A61K 35/28 (2006.01) A61P 43/00 (2006.01) C12N 15/09 (2006.01)
Patent
CA 2744289
The present invention relates to stem cells obtained by culturing monocytes in the presence of (i) M-CSF and (ii) at least one member selected from the group consisting of ganglioside and water-soluble plant-derived extract, thereby dedifferentiating the monocytes; a therapeutic agent for treating damaged cells, tissues or organs; a cell drug agent; a method of producing stem cells, a culture medium for dedifferentiating monocytes; a dedifferentiation inducing agent; a cell drug kit; a kit for producing dedifferentiated cells; and a pharmaceutical composition.
L'invention concerne une cellule souche produite par culture d'un monocyte en présence (i) de M-CSF et (ii) dau moins un composant choisi dans un groupe constitué par un ganglioside et un extrait végétal soluble dans l'eau pour dédifférencier le monocyte; un agent thérapeutique pour des maladies associées à des lésions de cellules, de tissus ou dorganes; un agent thérapeutique cellulaire; un procédé de production d'une cellule souche; un milieu de culture pour induire la dédifférenciation d'un monocyte; un agent d'induction de dédifférenciation; un kit pour une thérapie cellulaire ou un kit pour produire des cellules dédifférenciées, et une composition pharmaceutique.
Hirano Hisanobu
Ishiyama Hironobu
Ohkubo Yasushi
Sasaki Kenjiro
Marks & Clerk
Otsuka Pharmaceutical Co. Ltd.
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