Stem cells

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/00 (2006.01) C12N 5/071 (2010.01) A61K 35/12 (2006.01) A61K 48/00 (2006.01) C12N 5/10 (2006.01) C12P 21/00 (2006.01)

Patent

CA 2549930

The present invention relates to an isolated stem cell population wherein said stem cells are CD34+, capable of self regeneration, capable of differentiation into ectodermal, mesodermal and endodermal cells and capable of adhering to tissue-culture grade plastic as well as to methods of isolation of said cells, methods of culturing and differentiation thereof, the progeny of such methods of differentiation as well as uses, including therapeutic uses of the stem cells and their differentiated progeny.

L'invention concerne une population isolée de cellules souches selon laquelle lesdites cellules souches sont des cellules de type CD34?+¿. Les cellules de l'invention peuvent s'autorégénérer, se différencier en cellules ectodermiques, mésodermiques et endodermiques ; et adhérer au plastique présent dans des procédés de culture tissulaire. L'invention concerne également des procédés d'isolation desdites cellules, des procédés de culture et de différenciation de celles-ci, la progéniture issue desdits procédés de différenciation ainsi que leurs utilisations, notamment des utilisations thérapeutiques desdites cellules et de leur progéniture différenciée.

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