C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/074 (2010.01) C12N 5/077 (2010.01) A61K 8/99 (2006.01) A61K 35/12 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2493532
The invention relates to multipotent adult human stem cells which are characterized by the fact that they: i) have significant telomerase activity; ii) are of HLA phenotype class I negative; iii) have a normal karyotype; iv) are able to become quiescent; and v) are capable of sustained self-renewal during at least 130 doublings of the population.
L'invention concerne des cellules souches humaines multipotentes et adultes, caractérisées en ce qu'elles présentent: i) une activité télomérase significative, ii) un phénotype HLA Classe I négatif, iii) un caryotype normal, iv) une capacité à rentrer en quiescence, v) une capacité d'autorenouvellement conservée pendant au moins 130 doublements de population.
Ailhaud Gerard
Dani Christian
Rodriguez Anne-Marie
Centre National de La Recherche Scientifique
Smart & Biggar
Universite de Nice - Sophia Antipolis
Yves Saint-Laurent Parfums
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