Stent coated with a sustained-release drug delivery and...

A - Human Necessities – 61 – F

Patent

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A61F 2/06 (2006.01) A61K 9/00 (2006.01) A61K 31/192 (2006.01) A61K 31/505 (2006.01) A61K 31/513 (2006.01) A61K 31/58 (2006.01) A61K 47/32 (2006.01) A61K 47/34 (2006.01) A61L 17/00 (2006.01) A61L 29/16 (2006.01) A61L 31/10 (2006.01) A61L 31/16 (2006.01) A61P 43/00 (2006.01) A61K 9/70 (2006.01)

Patent

CA 2460920

An intraluminal medical device comprises a stent having a coating applied to at least part of an interior surface, an exterior surface, or both. The coating comprises a sustained release formulation of a combination of pharmaceutical compounds dispersed within a biologically tolerated polymer composition. The choice of the combination of pharmaceutical compounds are intended to reduce neointimal hyperplasia restenosis.

Un dispositif médical intraluminal comprend une prothèse endovasculaire présentant un revêtement appliqué sur au moins une partie d'une surface intérieure, d'une surface extérieure ou des deux. Le revêtement contient une formulation à libération prolongée d'une combinaison de composés pharmaceutiques dispersés à l'intérieur d'une composition polymère biologiquement tolérée. Le choix de la combinaison de composés pharmaceutiques permet de réduire la resténose hyperplasique de la néointima.

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