Stent tissue graft prosthesis

A - Human Necessities – 61 – F

Patent

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A61F 2/06 (2006.01)

Patent

CA 2506510

A stent tissue graft prosthesis for repairing, excluding and/or reinforcing a vessel, duct and the like in a patient. The prosthesis includes an inner expandable stent of which a tissue graft and preferably a multilayered tissue construct is disposed thereon for application to the host tissue of a vessel, duct and the like. The tissue construct includes an extracellular matrix material such as small intestine submucosa for remodeling the host tissue into the prosthesis. The prosthesis further includes an outer tubular member such as an outer expandable stent for retaining the tissue graft on the inner stent. The ends of the inner and outer stents are coincident with or extend beyond the ends of the tissue graft to prevent eversion or fold back of the tissue graft during withdrawal of a delivery catheter in a placement procedure.

L'invention porte sur une prothèse endovasculaire (20) de stents et de tissus utilisée pour la réparation, le remplacement ou le renforcement de vaisseaux, conduits ou autres. Ladite prothèse comporte: un stent intérieur (21) dilatable; un greffon de tissu (24) ou d'assemblage de tissus disposé sur le stent intérieur, s'appliquant sur le tissu hôte du vaisseau, conduit ou autre, et constitué d'un matériau matrice extracellulaire tel que de la muqueuse d'intestin grêle qui remodèle le tissu hôte; et un élément tubulaire (25) tel qu'un stent extérieur (44) dilatable maintenant le greffon sur le stent inférieur. Les extrémités des stents coïncident avec celles du greffon ou en dépassent, afin d'empêcher la réversion ou le repliement du greffon lors du retrait du cathéter de mise en place de la prothèse.

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