Stereochemical wortmannin derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 493/06 (2006.01) A61K 31/365 (2006.01) A61K 31/585 (2006.01) C07J 73/00 (2006.01)

Patent

CA 2193963

This invention relates to derivatives of Wortmannin and particularly to 11,17 substituted derivatives of Wortmannin, useful as PI-3-kinase inhibitors and as anti-tumor agents.

L'invention concerne des dérivés de la wortmannine et plus particulièrement à des dérivés de la wortmannine substitués en 11 et 17, utiles en tant qu'inhibiteurs de la PI-3-kinase et agents antitumoraux.

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