Stereoisomeric forms of n¬2-(4-carboxymethoxyphenyl)...

Details Stereoisomeric forms of n¬2-(4-carboxymethoxyphenyl)... Stereoisomeric forms of n¬2-(4-carboxymethoxyphenyl)...

C - Chemistry, Metallurgy

07

C

167/246, 260/514

C07C 229/22 (2006.01) A61K 31/135 (2006.01) A61K 31/195 (2006.01) A61K 31/215 (2006.01)

Patent

CA 1332741

ABSTRACT Novel Compounds: N-[2-(4-carboxymethoxyphenyl)-1-(R)-1-methylethyl]-2- (R)-2-hydroxy-2-(3-chlorophenyl)ethanamine or the methyl ester thereof, or a pharmaceutically acceptable salt thereof, ('the RR-isomer') optionally in admixture with N-[2-(4-carboxymethoxyphenyl)-1-(S)-1-methyl- ethyl]-2-(S)-2-hydroxy-2-(3-chlorophenyl)ethanamine, or the methyl ester thereof, or a pharmaceutically acceptable salt thereof, ('the SS-isomer') wherein the SS-isomer forms less than 50% by weight of the mixture of the RR- and SS- isomers; a process for preparing such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds and compositions in medicine and agriculture.

545543

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