Stereoselective alkylation of chiral 2-methyl-4-protected...

Details Stereoselective alkylation of chiral 2-methyl-4-protected... Stereoselective alkylation of chiral 2-methyl-4-protected...

C - Chemistry, Metallurgy

07

D

C07D 295/18 (2006.01) C07B 37/04 (2006.01) C07C 45/51 (2006.01) C07C 309/73 (2006.01) C07D 295/08 (2006.01) C07D 295/084 (2006.01) C07D 295/088 (2006.01) C07D 295/185 (2006.01) C07D 295/192 (2006.01) C07D 295/205 (2006.01)

Patent

CA 2480481

The present invention describes the synthesis of the following compounds in high stereochemical purity by a novel stereoselective alkylation of 2-methyl-4- protected piperazines using an inorganic base. (I)

Dans une forme de réalisation représentative, la présente invention concerne la synthèse du composé suivant et des composés similaires, avec une haute pureté stéréochimique, au moyen d'un nouveau processus d'alkylation stéréosélectif: (I). Processus d'alkylation stéréosélectif (I)

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