Stereoselective ring opening reactions

C - Chemistry – Metallurgy – 07 – B

Patent

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Details

C07B 53/00 (2006.01) C07B 57/00 (2006.01) C07C 29/10 (2006.01) C07C 31/20 (2006.01) C07C 31/28 (2006.01) C07C 31/42 (2006.01) C07C 33/035 (2006.01) C07C 33/26 (2006.01) C07C 41/03 (2006.01) C07C 41/26 (2006.01) C07C 43/13 (2006.01) C07C 43/23 (2006.01) C07C 45/64 (2006.01) C07C 49/24 (2006.01) C07C 67/29 (2006.01) C07C 69/30 (2006.01) C07C 269/06 (2006.01) C07C 271/16 (2006.01) C07D 301/32 (2006.01) C07D 303/04 (2006.01) C07D 303/08 (2006.01) C07D 303/22 (2006.01) C07D 303/32 (2006.01) C07D 303/36 (2006.01)

Patent

CA 2339618

The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting ~ ~ ~ ~ ~ ~ ~ ~ ~ alcohols carboxylic acids and thiols and a racemic or diastereomeric mixture

La présente invention concerne une synthèse chimique stéréosélective ou régiosélective. En l'occurrence, on prend un nucléophile appartenant au groupe de l'eau, des alcools, des acides carboxyliques et des thiols et on le fait réagir avec un mélange racémique ou diastéréomère à base d'un substrat cyclique en présence d'un catalyseur chiral non racémique de façon à réaliser une résolution cinétique du substrat cyclique. L'invention concerne également des résolutions cinétiques hydrolytiques de mélanges racémiques et diastéréomères d'époxydes.

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