Stereoselective synthesis of endothelin receptor antagonists

Details Stereoselective synthesis of endothelin receptor antagonists Stereoselective synthesis of endothelin receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 317/60 (2006.01) C07D 221/04 (2006.01) C07D 405/04 (2006.01) C07H 9/04 (2006.01) C07H 15/203 (2006.01) C07H 15/26 (2006.01)

Patent

CA 2236924

The present invention is directed to a synthetic route for preparing endothelium receptor antagonists of formulae (7B) and (7A) and to the chiral intermediates.

La présente invention concerne un procédé de préparation par synthèse d'antagonistes de récepteurs endothéliaux, lesquels antagonistes sont représentés par les formules générales (7A) et (7B). L'invention concerne également les intermédiaires chiraux correspondants.

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