Stereoselective synthesis of nucleoside analogues using...

Details Stereoselective synthesis of nucleoside analogues using... Stereoselective synthesis of nucleoside analogues using...

C - Chemistry, Metallurgy

07

D

C07D 411/04 (2006.01) C07D 407/04 (2006.01) C07D 409/04 (2006.01) C07D 473/00 (2006.01) C07D 497/08 (2006.01)

Patent

CA 2141029

The present invention relates to a process for producing predominantly pure cis nucleoside analogues using a novel bicyclic intermediate of formula (III), wherein X is S, or O; Y is S, CH2, O or CH(R); wherein R is azido or halogen; and Z is S or O.

La présente invention se rapporte à un procédé de production d'analogues de nucléosides cis essentiellement purs, au moyen d'un nouvel intermédiaire bicyclique de la formule (III); dans laquelle X représente S ou O; Y représente S, CH2, O ou CH(R), R représentant azido ou halogène; et Z représente S ou O.

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