Sterilized cyanoacrylate adhesive composition and a method...

Details Sterilized cyanoacrylate adhesive composition and a method... Sterilized cyanoacrylate adhesive composition and a method...

C - Chemistry, Metallurgy

09

J

C09J 4/04 (2006.01) A61L 2/08 (2006.01) A61L 24/06 (2006.01) C08K 5/13 (2006.01) C09J 4/00 (2006.01)

Patent

CA 2138689

-25- "STERILIZED CYANOACRYLATE ADHESIVE COMPOSITION, AND A METHOD OF MAKING SUCH A COMPOSITION" A curable cyanoacrylate adhesive composition intended for medical and/or veterinary uses is sterilized in liquid form by gamma irradiation. The composition comprises a) a cyanoacrylate monomer b) a combination of an anionic stabilizer and a free-radical stabilizer in amounts effective to stabilize the composition during irradiation and to stabilize the sterilized composition during storage prior to cure, wherein the free radical stabilizer is a selected phenolic antioxidant (but not including hydroquinone). The preferred free radical stabilizer is butylated hydroxyanisole. After irradiation the cyanoacrylate monomer is substantially ungelled.

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