Sterilized cyanoacrylate solutions containing thickeners

A - Human Necessities – 61 – L

Patent

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A61L 24/04 (2006.01) A61L 24/06 (2006.01)

Patent

CA 2380916

A method of making a sterile adhesive composition includes placing a mixture of a polymerizable adhesive monomer and a thickening agent in a container, sealing the container, and sterilizing the mixture and the container. The method provides superior viscosity for the monomer composition. The sterile adhesive composition is particularly useful as a medical adhesive and can comprise 1,1-disubstituted ethylene monomers, such as .alpha.-cyanoacrylates.

L'invention concerne un procédé de préparation d'une composition adhésive stérile, consistant à placer un mélange constitué d'un monomère adhésif polymérisable et d'un agent épaississant dans un récipient, à fermer hermétiquement le récipient, et à stériliser le mélange et le récipient. Ce procédé permet d'obtenir une plus grande viscosité dans la composition du monomère. Cette composition adhésive stérile est utilisée, en particulier, comme adhésif médical et peut comprendre des monomères d'éthylène 1,1-disubstitué, tels que les .alpha.-cyanoacrylates.

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