Sterilized plasma and plasma derivatives and process therefor

Details Sterilized plasma and plasma derivatives and process therefor Sterilized plasma and plasma derivatives and process therefor

A - Human Necessities

61

K

167/140, 167/103

A61K 35/16 (2006.01) A61L 2/00 (2006.01) C07K 14/755 (2006.01)

Patent

CA 1207229

ABSTRACT OF THE DISCLOSURE A mammalian blood plasma or plasma derivative substantially free of active hepatitis B or non-A, non-B viruses is disclosed, the plasma being characterized by the presence of factor VIII, the percent by weight of denatured factor VIII to the sum of undenatured factor VIII and denatured factor VIII being less than 50%. The plasma is sterilized by contact with a detergent, alcohol or ether, preferably a mixture of detergent and ether, usually followed by removal of the viral sterilizing agent.

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