Steroid 5-alpha-reductase inhibitors

C - Chemistry – Metallurgy – 07 – J

Patent

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167/192, 260/3

C07J 73/00 (2006.01) A61K 31/58 (2006.01) C07J 3/00 (2006.01) C07J 31/00 (2006.01)

Patent

CA 1325006

ABSTRACT OF THE DISCLOSURE STEROID 5-ALPHA-REDUCTASE INHIBITORS Invented are 4-aza-5-alpha-8(14)-17 substituted- androsten-3-ones having an 8(14), 7(8), or 16(17) double bond, optionally also having a 1(2) double bond, pharmaceutical compositions containing the compounds, and methods of using these compounds to inhibit steroid 5-alpha-reductase.

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