Steroid compounds

C - Chemistry – Metallurgy – 07 – J

Patent

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C07J 9/00 (2006.01) C07C 401/00 (2006.01) C07J 31/00 (2006.01) C07J 51/00 (2006.01) C07J 53/00 (2006.01) C07J 71/00 (2006.01)

Patent

CA 1334587

The present invention is directed to steroid compounds of the following general formulae (I), (II) and (III): Image (I) Image (II) (III) Image In the above formulae, R1 and R2 each represent a hydrogen atom or a hydroxyl-protecting group, R is a group of the formula -CH2-X (in which X is a substituent such as a hydroxyl group), a carboxyl group or a protected carboxyl group, A1 is an aryl group, a lower alkyl group or an aralkyl group, and z1 z2 z3 and Z4 each represent a hydrogen atom, a hydroxyl group or a protected hydroxyl group. The above steroid compounds are useful as intermediates for the synthesis of vitamin D3 derivatives having a hydroxyl group at the l.alpha.-position.

604714

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