Steroid cream formulation

Details Steroid cream formulation Steroid cream formulation

A - Human Necessities

61

K

167/159, 167/192

A61K 31/565 (2006.01) A61K 9/107 (2006.01) A61K 47/00 (2006.01)

Patent

CA 1326447

STEROID CREAM FORMULATION Abstract A steroid cream formulation which has enhanced physical and chemical stability is formed of (11.beta.,17.alpha.)-17-(ethylthio)-9.alpha.-fluoro-11.beta.-hydroxy- 17-(methylthio)androsta-1,4-dien-3-one (tipredane), and a vehicle containing as major ingredients glyceryl monostearate having an acid value of greater than 4, propylene glycol and water together with a sodium citrate or potassium citrate buffer, a non-acidic long chain fatty acid wax to impart proper consistency, and sodium metabisulfite as an antioxidant, together with emulsifiers, skin conditioners, emollients, lubricants and other conventional cream formulation ingredients.

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