Steroid receptor coactivator compositions and methods of use

Details Steroid receptor coactivator compositions and methods of use Steroid receptor coactivator compositions and methods of use

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C12N 15/63 (2006.01) C12N 15/67 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2231850

The present invention relates to SRC-1 polypeptides, nucleic acids encoding such polypeptides, cells, tissues and animals containing such nucleic acids, antibodies to such polypeptides, assays utilizing such polypeptides, and methods relating to all of the foregoing. Methods for enhancing and inhibiting transcription by providing SRC-1 polypeptides or fragments thereof to a cell.

Polypeptides coactivateurs 1 de récepteurs de stéroïdes (SRC-1), acides nucléiques codant lesdits polypeptides, cellules, tissus et animaux contenant lesdits acides nucléiques, anticorps contre lesdits polypeptides, dosages utilisant lesdits polypeptides et procédés concernant tous les éléments susmentionnés. Des procédés permettant de favoriser et d'inhiber la transcription en fournissant à une cellule des polypeptides SRC-1 ou des fragments desdits polypeptides sont également décrits.

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