Steroid sulfatase inhibitors and methods for making and...

C - Chemistry – Metallurgy – 07 – J

Patent

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Details

C07J 71/00 (2006.01) A61K 31/56 (2006.01) A61K 31/59 (2006.01) C07J 41/00 (2006.01)

Patent

CA 2361168

Novel sulfatase inhibitor compounds useful in the treatment of estrogen dependent illnesses are disclosed. These compounds generally comprise a steroid nucleus substituted at the C17 position. Methods for synthesizing these compounds and using them in the therapeutic and/or prophylactic treatment of a patient are also disclosed.

La présente invention concerne de nouveaux composés inhibiteurs de sulfatase utilisés dans le traitement de maladies dépendant des oestrogènes. Les composés précités comprennent généralement un noyau stéroïde substitué en position C17. L'invention se rapporte également à des procédés de synthèse et d'utilisation de ces composés dans le traitement thérapeutique et/ou prophylactique d'un patient.

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