Steroid sulphatase inhibitors

Details Steroid sulphatase inhibitors Steroid sulphatase inhibitors

C - Chemistry, Metallurgy

07

J

C07J 41/00 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2114630

Novel steroid sulphatase inhibitors are disclosed as well as pharmaceutical compositions containing them for use in the treatment of oestrone dependent tumours, especially breast cancer. The novel steroid sulphatase inhibitors are: sulphamate esters of formula (1), where R1 and R2 are each H, alkyl, alkenyl, cycloalkyl or aryl, or together represent an alkylene group option- ally containing a heteroatom e.g. -O- or -NH-; and -O-polycycle represents the residue of a polycyclic alcohol, preferably a sterol, most preferably a 3-sterol. Preferred compounds are oestrone-3- sulphamate and N,N-dimethyl oestrone-3-sulpha- mate.

Affiliated with

Also associated with

Rating

Steroid sulphatase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Steroid sulphatase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Steroid sulphatase inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1582732