Steroidal 17–-silyl ethers and process to corticoids and...

Details Steroidal 17–-silyl ethers and process to corticoids and... Steroidal 17–-silyl ethers and process to corticoids and...

C - Chemistry, Metallurgy

07

J

260/59, 260/9

C07J 5/00 (2006.01) C07J 1/00 (2006.01) C07J 7/00 (2006.01) C07J 41/00 (2006.01) C07J 51/00 (2006.01) C07J 71/00 (2006.01)

Patent

CA 1317283

STEROIDAL 17.alpha.-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES ABSTRACT 17.alpha.-Cyano-17.alpha.-hydroxy steroids (I) are transformed to 17.alpha.-halosilyl ethers (II) which are intermediates useful in the production of progesterones (V), 17-hydroxyprogesterones (VI), corticoids (VII) and 21-halo corticoids (III) which can readily be transformed to cor- ticoids (VII).

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