Steroidal compounds as steroid sulphatase inhibitors

C - Chemistry – Metallurgy – 07 – J

Patent

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Details

C07J 63/00 (2006.01) A61K 31/56 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2636431

There is provided a compound having Formula (I): wherein G is a fluorocarbyl group, and wherein R1 is any one of a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group, capable of inhibiting steroid sulphatase.

L'invention concerne un composé de formule (I) où G représente un groupe fluorocarbyle et où R1 peut représenter soit un groupe sulphamate, soit un groupe phosphonate, soit un groupe thiophosphonate, soit un groupe sulphonate, soit un groupe sulphonamide, capables d'inhibiter la stéroïde sulfatase.

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