Steroidal erythropoietic agents and therapeutic compositions...

Details Steroidal erythropoietic agents and therapeutic compositions... Steroidal erythropoietic agents and therapeutic compositions...

C - Chemistry, Metallurgy

07

J

260/21, 260/51

C07J 1/00 (2006.01)

Patent

CA 1077924

ABSTRACT OF THE DISCLOSURE The invention relates to a compound selected from the group consisting of the 3-ester and 3-ethers of 3.beta.-hydroxy-5.beta.-oestran-17-one and the corresponding 3.alpha.-epimer. On administration to humans and other warm- blooded animals these compounds simulate erythropoiesis. These novel steroids are particularly advantageous in that they exhibit an unexpected low level of pyrogenicity as compared to etiocholanolone, known pyrogen.

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