C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 9/00 (2006.01) A61K 31/56 (2006.01) A61K 31/575 (2006.01) C12N 15/00 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2718494
The present invention relates to steroidal ligands for use in nuclear receptor- based inducible gene expression systems. The invention further relates to methods of modulating the expression of genes of interest with a system containing one or more nuclear receptor complexes and one or more steroidal ligands. Further aspects include ligand compositions including therapeutic compositions.
La présente invention concerne des ligands stéroïdes destinés à être utilisés dans des systèmes dexpression génique inductibles basés sur un récepteur nucléaire. Linvention concerne en outre des procédés de modulation de lexpression des gènes dintérêt avec un système contenant un ou plusieurs complexes de récepteur nucléaire et un ou plusieurs ligands stéroïdes. Dautres aspects de linvention incluent des compositions de ligand qui comprennent des compositions thérapeutiques.
Hormann Robert E.
Lapenna Silvia
Intrexon Corporation
Mbm Intellectual Property Law Llp
LandOfFree
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