Steroidal liposomes

Details Steroidal liposomes Steroidal liposomes

A - Human Necessities

61

K

167/159, 167/163

A61K 9/52 (2006.01) A61K 9/127 (2006.01) A61K 31/59 (2006.01)

Patent

CA 1262334

ABSTRACT OF THE DISCLOSURE A method for administering a compound in vivo in which the compound entrapped in a liposome, the bilayers of which comprise a salt form of an organic acid derivative of a sterol. The bilayers may comprise a tris(hydroxymethyl)aminomethane salt form of an organic acid derivative of a sterol. The invention also provides a method for the entrapment of a water-insoluble compound in sterol vesicles; a composition comprising the tris(hvdroxymethyl)aminomethane salt of cholesteryl hemisuccinate and an antifungal compound; and a method of treating a fungal infection.

491321

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