Steroidic aromatase inhibitors

Details Steroidic aromatase inhibitors Steroidic aromatase inhibitors

C - Chemistry, Metallurgy

07

J

167/198, 260/37

C07J 41/00 (2006.01) A61K 31/565 (2006.01) C07J 1/00 (2006.01)

Patent

CA 1252085

ABSTRACT The invention relates to 6-substituted androsta- -1,4-diene-3,17-dione derivatives wherein the 6 substituent is an azido, amino or substituted amino group. The invention provides also a process for preparing the said compounds and pharmaceutical compositions containing same. The compounds of the invention are useful aromatase inhibitors and can be used, e.g., in the treatment of hormone- dependent tumors.

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