Steroids as agonists for fxr

Details Steroids as agonists for fxr Steroids as agonists for fxr

C - Chemistry, Metallurgy

07

J

C07J 9/00 (2006.01) A61K 31/575 (2006.01) A61P 9/10 (2006.01) C07J 75/00 (2006.01)

Patent

CA 2440680

The invention relates to compounds of formula (I) wherein R is ethyl, propyl or allyl, and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof. The compounds of formula (I) are useful as FXR agonists.

L'invention concerne des composés de formule (I) dans laquelle R est éthyle, propyle ou allyle, ainsi que des sels, des solvates ou des conjugués d'acides aminés pharmaceutiquement acceptables de ces derniers. Les composés de formule (I) sont utiles en tant qu'agonistes de FXR.

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