Steroids as neurochemical stimulators of the vno to...

C - Chemistry – Metallurgy – 07 – J

Patent

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C07J 71/00 (2006.01) A61K 31/56 (2006.01) A61K 31/565 (2006.01) A61K 31/57 (2006.01) A61K 31/58 (2006.01) C07J 1/00 (2006.01) C07J 3/00 (2006.01) C07J 7/00 (2006.01) C07J 9/00 (2006.01) C07J 13/00 (2006.01) C07J 17/00 (2006.01) C07J 21/00 (2006.01) C07J 31/00 (2006.01)

Patent

CA 2260253

The invention relates to a method of alleviating the symptoms of PMS and anxiety. The method comprises nasally administering a steroid which is a human vomeropherin, such that the vomeropherin binds to a specific neuroepithelial receptor. The steroid or steroids is/are preferably administered in the form of a pharmaceutical composition containing one or more pharmaceutically acceptable carriers.

Cette invention concerne un procédé permettant de soulager le symptôme prémenstruel ainsi que les symptômes de l'anxiété. Ce procédé consiste à administrer par voie nasale un stéroïde consistant en une vomérophérine d'origine humaine, ceci de manière à ce que cette dernière puisse se lier à un récepteur neuro-épithélial spécifique. Le ou les stéroïdes sont de préférence administrés sous forme d'une composition pharmaceutique qui comprend un ou plusieurs excipients acceptables sur le plan pharmaceutique.

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