Steroids for cancer treatment

C - Chemistry – Metallurgy – 07 – J

Patent

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Details

C07J 3/00 (2006.01)

Patent

CA 2552843

The present invention relates to novel compounds which are 7.alpha.- substituted 17-alkylene-16.alpha.-hydroxy steroidal estrogens. This invention specifically relates to estrogen derivatives which contain 7.alpha.- substituents and which exhibit anti-estrogenic properties. The present invention also relates to use of said compounds as a medicament, and for the treatment of estrogen dependent disorders, a pharmaceutical composition comprising one or more of said compounds and a method of treatment.

L'invention concerne des composés : des oestrogènes stéroïdaux 7?-substitués 17-alkylène-16?-hydroxy. Plus précisément, l'invention concerne des dérivés d'oestrogènes renfermant des substituants en 7? et possédant des propriétés anti-oestrogènes. L'invention concerne également l'utilisation de ces composés comme médicament et pour le traitement de troubles dépendants des oestrogènes, une composition pharmaceutique comprenant un ou plusieurs de ces composés et une méthode de traitement.

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