Steroids for treating menopausal complaints

C - Chemistry – Metallurgy – 07 – J

Patent

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Details

C07J 1/00 (2006.01) A61K 31/56 (2006.01) A61K 31/565 (2006.01) C07J 11/00 (2006.01) C07J 21/00 (2006.01) C07J 33/00 (2006.01) C07J 41/00 (2006.01) C07J 51/00 (2006.01)

Patent

CA 2155532

A use of a steroid having general formula (I), wherein R1 represents O, (H, OH), or two hydrogen atoms; R2 is hydroxy, optionally etherified or esterified; R3 is (2-6 C) alkynyl, optionally substituted with hydroxy; R4 is CN or one of the hydrocarbon groups selected from (1-6 C) alkyl, (1-6 C) alkoxy, (2-6 C) alkenyl, (2-6 C) alkynyl, and (2-6 C) alkylidene, each of said hydrocarbon groups may optionally be substituted with halogen, hydroxy or (1-6 C) alkoxy; and R5 is hydrogen or (1-6 C) alkyl, for the manufacture of a medicament for the treatment or prevention of menopausal complaints, especially osteoporosis.

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