Steroids having a spiro cycle in position 17, their process...

C - Chemistry – Metallurgy – 07 – J

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C07J 21/00 (2006.01) C07J 31/00 (2006.01) C07J 33/00 (2006.01) C07J 41/00 (2006.01) C07J 43/00 (2006.01)

Patent

CA 1299169

PRECIS DE LA DIVULGATION: L'invention concerne les produits (I): Image (I) dans laquelle R1 est un aryle ou aralkyle, R2 est un radical hydrocarboné (1 à 18 carbones), les pointillés indiquent une liaison éventuelle, les cycles A, B et C représentent: Image R' et R" = H, alcoyle (1 à 4 carbones), Re = H, alcoyle (1 a 6 carbones), acyle (1 à 7 carbones), et leurs sels pharmaceutiquement acceptables. L'invention concerne également un procédé pour la préparation de ces produits. Ces produits de formule (I) sont utiles comme médicament montrant des activités progestomimétiques ou anti-progestomimétiques, androgènes ou anti-androgènes.

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