Steroids substituted in position 11, method of preparation,...

Details Steroids substituted in position 11, method of preparation,... Steroids substituted in position 11, method of preparation,...

C - Chemistry, Metallurgy

07

J

C07J 41/00 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2275955

The invention concerns steroid compounds of general formula (I) in which n = 2, 3, <u>either</u> R¿1? and R¿2? = H, (C¿1?-C¿4?) alkyl, <u>or</u> R¿1? and R¿2? form with nitrogen a heterocyclic compound, X = OH optionally esterified, Y = (C¿1?-C¿4?)alkyl, and their additive salts, the method for preparing them, their application as medicine and the pharmaceutical compositions containing them.

L'invention a pour objet des composés stéroïdes de formule générale (I) dans laquelle n = 2, 3, <u>soit</u> R1 et R2 = H, (C1-C4)alkyle, <u>soit</u> R1 et R2 forment avec l'azote un hétérocycle, X = OH éventuellement estérifié, Y = (C1-C4)alkyle, ainsi que leurs sels d'addition, leur procédé de préparation, leur application comme médicament et les compositions pharmaceutiques les renfermant.

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