Steroids which inhibit angiogenesis

Details Steroids which inhibit angiogenesis Steroids which inhibit angiogenesis

C - Chemistry, Metallurgy

07

J

C07J 5/00 (2006.01) A61K 31/56 (2006.01) C07J 3/00 (2006.01) C07J 7/00 (2006.01) C07J 9/00 (2006.01) C07J 31/00 (2006.01) C07J 51/00 (2006.01) C07J 71/00 (2006.01)

Patent

CA 2081205

Novel angiostatic .DELTA.4,9(11)-steroids (I), C21-oxygenated steroids (II) and other known steroidal compounds have been found to be useful in treating angiogenesis in mammals who have a need for the same. These steroids are useful in treating diseases of neovascularization such as cancer, diabetes and arthritis.

De nouveaux stéroïdes DELTA4,9(11) angiostatiques de la formule (I), des stéroïdes oxygénés C21 (II) et d'autres composés stéroïdiens connus se sont avérés utiles pour le traitement de l'angiogenèse chez des mammifères ayant besoin d'un tel traitement. Ces stéroïdes sont utiles pour le traitement de maladies de néoformation de vaisseaux telles que cancer, diabète et arthrite.

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