Stilbene derivatives and their use for binding and imaging...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 217/80 (2006.01) A61K 51/04 (2006.01)

Patent

CA 2591534

This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits.

L'invention concerne un procédé d'imagerie de dépôts amyloïdes et des composés marqués, ainsi que des procédés de production de composés marqués présentant une utilité dans l'imagerie de dépôts amyloïdes. L'invention concerne également des composés et des procédés de production de composés destinés à inhiber l'agrégation de protéines amyloïdes formant des dépôts amyloïdes, ainsi qu'un procédé d'acheminement d'un agent thérapeutique au niveau de dépôts amyloïdes.

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