Stilbene derivatives and their use for binding and imaging...

Details Stilbene derivatives and their use for binding and imaging... Stilbene derivatives and their use for binding and imaging...

C - Chemistry, Metallurgy

07

D

C07D 333/10 (2006.01) A61K 31/015 (2006.01) A61K 31/04 (2006.01) A61K 31/045 (2006.01) A61K 31/136 (2006.01) A61K 31/34 (2006.01) A61K 31/381 (2006.01) A61K 31/40 (2006.01) A61K 31/429 (2006.01) A61K 51/00 (2006.01) A61K 51/04 (2006.01) C07C 211/49 (2006.01) C07D 307/36 (2006.01) C07F 13/00 (2006.01)

Patent

CA 2456411

This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits.

L'invention concerne un procédé d'imagerie des dépôts amyloïdes et des composés étiquetés, ainsi que des procédés de préparation des composés étiquetés utiles dans l'imagerie de dépôts amyloïdes. L'invention concerne également des composés et des procédés de préparation de composés d'inhibition de l'agrégation de protéines amyloïdes, aux fins de formation de dépôts amyloïdes, ainsi qu'un procédé d'administration d'un agent thérapeutique à des dépôts amyloïdes.

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