Stimulation of an antitumor t-cell response using...

Details Stimulation of an antitumor t-cell response using... Stimulation of an antitumor t-cell response using...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61B 10/00 (2006.01) A61K 31/70 (2006.01) A61K 39/00 (2006.01) C07K 16/42 (2006.01) C12Q 1/00 (2006.01) G01N 33/569 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2139743

Anti-idiotypic antibodies containing internal images which mimic tumor associated antigens are useful as vaccines to sti- mulate a T-cell immune response in a tumor bearing subject or in a subject at risk for malignancy. The antibodies are adminis- tered and the T-cell response of the subject is monitored in order to assess the efficacy of the protocols and/or the antibodies are administered in combination with an adjuvant known to enhance T-cell responses.

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