Stimulation of hair growth by peptide-copper complexes

Details Stimulation of hair growth by peptide-copper complexes Stimulation of hair growth by peptide-copper complexes

A - Human Necessities

61

K

A61K 8/64 (2006.01) A61Q 7/00 (2006.01)

Patent

CA 2192944

Peptide-copper complexes are disclosed which stimulate the growth of hair on warm-blooded animals. In one aspect of this invention, the peptide-copper complexes are dipeptides or tripeptides chelated to copper at a molar ratio ranging from about 1:1 to 3:1, with the second position of the peptide from the amino terminus being histidine, arginine or a derivative thereof. The peptide-copper complexes may be formulated for administration by, for example, topical application or injection. Any affliction associated with hair loss, including hair loss associated with both androgenetic and secondary alopecia, may be treated with the peptide-copper complexes of this invention.

L'invention concerne des complexes constitués de cuivre et d'un peptide stimulant la croissance capillaire chez les animaux à sang chaud. Dans un mode de réalisation, ces complexes sont des dipeptides ou des tripeptides chélatés au cuivre selon un rapport molaire situé dans une plage d'environ 1:1 à 3:1, la deuxième position du peptide depuis la terminaison amino étant l'histidine, l'arginine ou un de leurs dérivés. On peut formuler ces complexes afin de les administrer, par exemple localement, ou par injection. Ils permettent de traiter des affections associées à la perte des cheveux, y compris la perte des cheveux associée à une alopécie à la fois androgénétique et secondaire.

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