Stimulation of vascularization with vegf-b

Details Stimulation of vascularization with vegf-b Stimulation of vascularization with vegf-b

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2451311

VEGF-B is shown to be needed for cardiac muscle revascularization after heart infarction, and methods of promoting or stimulating vascular development, e.g. angiogenesis and/or arteriogenesis, particularly in ischemic mammals, are disclosed.

Il s'est révélé que VEGF-B est nécessaire à la revascularisation du muscle cardiaque suite à un infarctus; l'invention concerne aussi des procédés pour favoriser ou stimuler le développement vasculaire, p.ex., l'angiogenèse et/ou l'artérogenèse, notamment chez des mammifères ischémiques.

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