Stimuli-responsive systems for controlled drug delivery

Details Stimuli-responsive systems for controlled drug delivery Stimuli-responsive systems for controlled drug delivery

A - Human Necessities

61

K

A61K 45/00 (2006.01) A61K 9/14 (2006.01)

Patent

CA 2509382

A method of delivering a therapeutic agent by providing a cross-linked polymer encapsulating the therapeutic agent to a site in a patient. The degradation rate of the cross-linked polymer is correlated with a local concentration of an indicator, and the therapeutic agent is released as the cross-linked polymer degrades.

L'invention porte sur un procédé d'administration d'un agent thérapeutique qui consiste à produire un polymère réticulé encapsulant l'agent thérapeutique sur un site chez un patient. La vitesse de dégradation du polymère réticulé est mise en corrélation avec une concentration locale d'un indicateur, et la libération de l'agent thérapeutique s'effectue au moment de la dégradation du polymère réticulé.

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