Sting (stimulator of interferon genes), a regulator of...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) C12N 15/113 (2010.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) A61K 39/12 (2006.01) A61K 39/39 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) C40B 40/10 (2006.01) G01N 33/50 (2006.01) C07K 14/52 (2006.01) C12N 15/19 (2006.01)

Patent

CA 2735710

Novel molecules termed STING which include nucleic acids, polynucleotides, oligonucleotides, peptides, mutants, variants and active fragments thereof, modulate innate and adaptive immunity in a subject. STING compositions are useful for the treatment of an immune-related disorder, including treating and preventing infection by modulating immunity

La présente invention concerne de nouvelles molécules appelées STING qui comprennent des acides nucléiques, des polynucléotides, des oligonucléotides, des peptides, des mutants, des variants et des fragments actifs de ceux-ci, qui modulent limmunité innée et adaptative chez un sujet. Des compositions de STING sont utiles pour le traitement dun trouble immunitaire, comprenant le traitement et la prévention dune infection par modulation de limmunité.

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