Storage-stable ophthalmic compositions comprising diclofenac...

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 31/195 (2006.01) A61K 31/197 (2006.01) A61K 31/535 (2006.01)

Patent

CA 2295061

The invention relates to stable ophthalmic preparations including the penetrant antiphlogistic diclofenac or salts thereof and the penetrant antibiotic ofloxacin present in the form of the racemate, an enantiomer, particularly levofloxacin, or the corresponding hydrochloride thereof. The preparations may be used for treating eye infections and/or inflammations and for preventing infections before and after eye surgery.

L'invention concerne des préparations ophtalmiques stables comprenant du diclofénac, qui est un antiphlogistique pénétrant, ou bien des sels de celui-ci, et de l'ofloxacine, qui est un antibiotique également pénétrant et qui est présente sous la forme de son racémate, d'un de ses énantiomères, en particulier de la lévofloxacine, ou bien de l'hydrochlorure correspondant. Ces préparations peuvent être utilisées pour le traitement d'infections et/ou d'inflammations de l'oeil, ainsi que pour la prévention des infections avant et après des opérations de l'oeil.

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