Storage-stable, quick-disintegrating pressed shapes...

Details Storage-stable, quick-disintegrating pressed shapes... Storage-stable, quick-disintegrating pressed shapes...

A - Human Necessities

61

K

167/166

A61K 47/00 (2006.01) A61K 9/20 (2006.01) A61K 9/50 (2006.01)

Patent

CA 1239348

Storage-stable, quick-disintegrating pressed shapes containing pharmaceutical active substances Abstract Storage stable, quick-disintegrating pressed shapes containing pharmaceutical active substances, which shapes consist substantially of a compressed mixture of a) an effective amount of a pharmaceutical active substance in granular form, which is coated with a coating material comprising essentially a homogeneous mixture of a poly(H + meth)-acrylic acid-(methyl + ethyl) ester insoluble but dispersible in water and an ethyl cellulose insoluble but dispersible in water, the weight ratio of the acrylic acid ester to ethyl cellulose being 2.5 : 1 to 5 : 1; b) talcum; and c) colloidal silicon dioxide, and crosslinked polyvinylpoly- pyrrolidone as the disintegrating agent having a high disintegrating capacity and good binding properties.

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