Strains of bacteria and pharmaceutical composition...

Details Strains of bacteria and pharmaceutical composition... Strains of bacteria and pharmaceutical composition...

C - Chemistry, Metallurgy

12

N

C12N 1/20 (2006.01) A61K 35/74 (2006.01)

Patent

CA 2198518

Strains of bacteria characterized by exhibiting: (a) a 70- dehydroxylase activity of less than 50%, and (b) a bile acid deconjugation activity of less than 50%, and descendants, mutants and derivatives thereof preserving activities (a) and (b); and a pharmaceutical composition comprising one or more of such strains and useful of same for preventing and treating deseases associated with or caused by an altered metabolism of bile acids.

Souches de bactéries caractérisées par : a) une activité de la 70-déshydroxylase inférieure à 50 %; b) une activité de déconjugaison de l'acide biliaire, inférieure à 50 %; leurs descendants, mutants et dérivés préservant les activités a) et b); composition pharmaceutique renfermant une ou plusieurs de ces souches, permettant de prévenir et de traiter les maladies associées à un métabolisme altéré des acides biliaires ou causées par ce dernier.

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