C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
195/1.37
C12N 1/19 (2006.01) C12N 15/81 (2006.01)
Patent
CA 1313634
3285P/0064B 17375 TITLE OF THE INVENTION IMPROVED STRAINS OF YEAST FOR THE EXPRESSION OF HETEROLOGOUS GENES ABSTRACT OF THE DISCLOSURE The GAL4 protein is rate-limiting in quantity as a positive regulator for galactose- inducible promoters in strains of yeast. Novel strains are described in which the GAL4 protein can be overproduced in a regulatable fashion. These strains are useful for the regulatable expression in yeast of heterologous genes whose expression is driven by a galactose-inducible promoter.
541765
Ellis Ronald W.
Hofmann Kathryn J.
Hopper James E.
Schultz Loren D.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
Research Corporation Technologies Inc.
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