Strains of yeast for the expression of heterologous genes

C - Chemistry – Metallurgy – 12 – N

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195/1.37

C12N 1/19 (2006.01) C12N 15/81 (2006.01)

Patent

CA 1313634

3285P/0064B 17375 TITLE OF THE INVENTION IMPROVED STRAINS OF YEAST FOR THE EXPRESSION OF HETEROLOGOUS GENES ABSTRACT OF THE DISCLOSURE The GAL4 protein is rate-limiting in quantity as a positive regulator for galactose- inducible promoters in strains of yeast. Novel strains are described in which the GAL4 protein can be overproduced in a regulatable fashion. These strains are useful for the regulatable expression in yeast of heterologous genes whose expression is driven by a galactose-inducible promoter.

541765

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