C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 39/09 (2006.01) C07K 14/315 (2006.01) C12N 5/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2269663
The present invention relates to novel vaccines for the prevention or attenuation of infection by Streptococcus pneumoniae. The invention further relates to isolated nucleic acid molecules encoding antigenic polypeptides of Streptococcus pneumoniae. Antigenic polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention additionally relates to diagnostic methods for detecting Streptococcus nucleic acids, polypeptides and antibodies in a biological sample.
La présente invention concerne des préparations vaccinales destinées à la prévention ou la lutte contre l'infection par Streptococcus pneumoniae. L'invention concerne également des molécules d'acide nucléiques qui ont été isolées et qui codent des polypeptides antigènes de Streptococcus pneumoniae. L'invention concerne aussi, d'une part des polypeptides antigènes tels que des vecteurs et des cellules hôtes, et d'autre part des procédés de production correspondants. L'invention concerne enfin des techniques de diagnostic permettant de détecter des acides nucléiques, des polypeptides et des anticorps de Streptococcus dans un échantillon biologique.
Choi Gil H.
Hromockyj Alex
Johnson L. Sydnor
Kunsch Charles A.
Gowling Lafleur Henderson Llp
Human Genome Sciences Inc.
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