Streptococcus pyogenes virulence genes and proteins and...

A - Human Necessities – 61 – K

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A61K 39/09 (2006.01) A61K 38/16 (2006.01) C07K 14/315 (2006.01) C07K 16/12 (2006.01) C12N 1/21 (2006.01) C12N 15/31 (2006.01) C12Q 1/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2397710

A series of genes from Streptococcus pyogenes are shown to encode products which are implicated in virulence. The identification of these genes therefore allows attenuated microorganisms to be produced. Furthermore, the genes or their encoded products can be used in the manufacture of vaccines for therapeutic application.

Une série de gènes de Streptococcus pyogenes codent des produits impliqués dans la virulence. L'identification de ces gènes permet ainsi la production de microorganismes atténués. De plus, les gènes ou leurs produits codés peuvent être utilisés dans la fabrication de vaccins destinés à des applications thérapeutiques.

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