Streptovaricinone c derivatives

C - Chemistry – Metallurgy – 07 – D

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260/237.1

C07D 225/08 (2006.01)

Patent

CA 1056825

ABSTRACT OF THE DISCLOSURE The present invention provides antibiotics which are streptovaricinone C derivatives of the formula (III) Image and aldol condensation products thereof where Z is selected from a C1-12 alkyl, aryl, hydroxyalkyl, chloroalkyl, a alkenyl, ketonyl, furyl-oxoalkyl, thienyl-oxoalkyl, a phenyl-oxoalkyl, carbamylalkyl, benzyl, phenoxyalkyl, cyanoalkyl, phenethyl, benzoyl- oxyethyl, p-chlorophenyl-oxoalkyl, p-methoxyphenyl-oxoalkyl, p-nitrobenzyl, p-methylbenzyl, alkanoyl, benzoyl, benzenesulfonyl, an alkylsulfonyl, phenoxycarbonyl, thienyl carbonyl or an alkoxycarbonyl group.

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