C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2442036
The invention provides a protein which is a stress-responsive activator of the p300 protein, and nucleic acid sequences encoding the protein. The protein performs a key role in facilitating stress-responsive protein-protein interactions within the p300 co-activator complex. The STRAP protein facilitates the interaction of other proteins in the p300 complex, and is thus a target for assays for modulators of the complex.
L'invention concerne une protéine qui constitue un activateur sensible au stress de la protéine p300, ainsi que des séquences d'acides nucléiques qui codent pour la protéine. Cette protéine joue un rôle clé dans les interactions protéine sensible au stress-protéine dans le complexe de coactivateur de p300. La protéine STRAP facilite l'interaction d'autres protéines avec le complexe p300, et constitue ainsi une cible pour des dosages de modulateurs du complexe.
Demonacos Constantinos
Krstic-Demonacos Marija
La Thangue Nicholas Barrie
Demonacos Constantinos
Fetherstonhaugh & Co.
Krstic-Demonacos Marija
La Thangue Nicholas Barrie
The University Court Of The University Of Glasgow
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