Stretch-activated cation channel and antisense...

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 21/00 (2006.01) A61K 31/70 (2006.01) C07H 21/04 (2006.01) C07K 14/705 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2202881

An antisense oligonucleotide of 10 to 35 nucleotides in length that can hybridize with a region of the .alpha.1 subunit of the SA-Cat channel gene DNA or mRNA is provided, together with pharmaceutical compositions containing and methods utilizing such antisense oligonucleotide.

Oligonucléotide antisens d'une longueur de 10 à 35 nucléotides qui peuvent s'hybrider avec une région de la sous-unité .alpha.¿1? de l'ADN ou de l'ARNm du gène du canal à cations activé par extension, compositions pharmaceutiques contenant ledit oligonucléotide antisens et procédés l'utilisant.

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